Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468485 | 0.81 | MAPK14 (0.55) | GUSBPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL9223207 | 0.78 | PIN1 (0.53) | GUSBKDM4ENPC1CRHBPRAB9A | |
| SCHEMBL6473195 | 0.75 | TARBP2 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2ALPL | |
| SCHEMBL9220606 | 0.73 | MEN1 (0.52) | GUSBKDM4ENPC1CRHBPRAB9A | |
| SCHEMBL7989339 | 0.72 | MAPK14 (0.46) | DHODHGUSBKDM4EMCL1PIN1 | |
| SCHEMBL7989925 | 0.71 | MAPK14 (0.62) | KDM4ENPC1RAB9ASMN1; SMN2CHEK2 | |
| SCHEMBL7977996 | 0.71 | TRPV1 (0.49) | CHEK2PIN1MAPK14GCGRMMP2 | |
| SCHEMBL7989653 | 0.71 | MAPK14 (0.55) | GUSBKDM4ENPC1RAB9AMAPK14 | |
| SCHEMBL2948138 | 0.70 | MAPK13 (0.58) | GUSBKDM4EMAPK14GCGR | |
| SCHEMBL7991890 | 0.69 | BRAF (0.48) | CHEK2PIN1MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438296-A2 | 1H-IMIDAZOLE DERIVATIVES HAVING CB1 AGONISTIC, CB1 PARTIAL AGONISTIC OR CB1- ANTAGONISTIC ACTIVITY | Solvay Pharmaceuticals B.V. (NL) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003027076-A2 | 1H-IMIDAZOLE DERIVATIVES HAVING CB1 AGONISTIC, CB1 PARTIAL AGONISTIC OR CB1- ANTAGONISTIC ACTIVITY | SOLVAY PHARMACEUTICALS B.V. (NL) | 2003-04-03 | — | — | WO | disclosed |