Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.46 |
| ▸ | GCGR | P47871 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992002 | 0.89 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7995288 | 0.88 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6366542 | 0.88 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7988191 | 0.87 | NPBWR1 (0.53) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7995390 | 0.87 | MAPK14 (0.48) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7989517 | 0.83 | MAPT (0.49) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7990062 | 0.82 | SIRT2 (0.53) | TRPV1TP53MAPT | |
| SCHEMBL6631782 | 0.79 | PIN1 (0.67) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6469444 | 0.79 | MAPK13 (0.68) | TRPV1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL28158003 | 0.78 | PIN1 (0.71) | PIN1PARP1TNKSTNKS2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |