Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602523 | 1.00 | APLNR (0.36) | APLNRADRA2AADRA2BADRA2CNNMT | |
| SCHEMBL27213761 | 0.76 | NNMT (0.61) | NNMTLMNAGFERKMT2AL3MBTL1 | |
| SCHEMBL27213728 | 0.75 | ALDH1A1 (0.38) | ADRA2AADRA2BADRA2CGAA | |
| SCHEMBL2469953 | 0.74 | NNMT (0.59) | APLNRNNMTLMNAKMT2A | |
| SCHEMBL18735817 | 0.74 | NOS1 (0.36) | APLNRADRA2AADRA2BADRA2CNNMT | |
| SCHEMBL1580849 | 0.73 | P2RX7 (0.50) | KMT2ARAB9A | |
| SCHEMBL1580848 | 0.73 | P2RX7 (0.50) | KMT2ARAB9A | |
| SCHEMBL4947126 | 0.69 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CKMT2ARAB9A | |
| SCHEMBL10312544 | 0.69 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CKMT2ARAB9A | |
| SCHEMBL10312534 | 0.69 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821972-B2 | ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS | PFIZER INC. | 2004-11-23 | — | — | US | disclosed |