Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL28096005 | 0.94 | HSD17B1 (0.42) | HSD17B1HSD17B2ESR1ESR2MEN1 | |
| SCHEMBL13367414 | 0.83 | TSHR (0.46) | HSD17B1HSD17B2LMNATP53MAPT | |
| SCHEMBL20384981 | 0.83 | TSHR (0.41) | MEN1TSHRKMT2ASIGMAR1ACHE | |
| SCHEMBL2198610 | 0.83 | TSHR (0.41) | MEN1TSHRKMT2ASIGMAR1ACHE | |
| SCHEMBL28032010 | 0.82 | ESR1 (0.43) | HSD17B1HSD17B2ESR1ESR2LMNA | |
| SCHEMBL8652577 | 0.80 | CYP3A4 (0.46) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL21549230 | 0.80 | CES1 (0.42) | MEN1TSHRKMT2ASIGMAR1APP | |
| SCHEMBL20818184 | 0.80 | CES2 (0.42) | MEN1NPC1LMNATSHRMAPK1 | |
| SCHEMBL21479978 | 0.80 | TAAR1 (0.39) | HSD17B1HSD17B2USP2SIGMAR1MAPK13 | |
| SCHEMBL11569334 | 0.79 | ALDH1A1 (0.55) | HSD17B1HSD17B2LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205391-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-09-26 | — | — | CN | disclosed |
| US-20040242891-A1 | Production of keto acids | CAMPBELL JONATHAN (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| US-6635602-B1 | Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-21 | — | — | US | disclosed |
| US-6566302-B1 | For use in heat sensitive and pressure sensitive recording materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-20 | — | — | US | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |
| EP-1107972-B1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | CIBA SC HOLDING AG (CH) | 2003-01-02 | — | — | EP | disclosed |
| EP-1115579-B1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SC HOLDING AG (CH) | 2002-11-20 | — | — | EP | disclosed |
| EP-0853079-B1 | Production of keto acids | CIBA SC HOLDING AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1115579-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Ciba SC Holding AG (CH) | 2001-07-18 | — | — | EP | disclosed |
| EP-1107972-A1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | Ciba SC Holding AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000026037-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000012318-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012513-A1 | NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| US-5925787-A | Production of keto acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0853079-A1 | Production of keto acids | Ciba SC Holding AG (CH) | 1998-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | PKLR, KHK, ME1 | HSD17B1 382/4885HSD17B2 640/4885ESR1 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.