Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891641 | 0.85 | KMT2A (0.35) | RAB9AKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL4897641 | 0.83 | KMT2A (0.36) | RAB9AKMT2AHPGDLMNASMN1; SMN2 | |
| SCHEMBL4902695 | 0.82 | PSIP1 (0.35) | RAB9AKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL4900892 | 0.79 | KMT2A (0.42) | RAB9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4895537 | 0.79 | TDP1 (0.35) | RAB9AKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL6873824 | 0.77 | PTGS2 (0.36) | KMT2AMEN1MAPTKAT6A | |
| SCHEMBL4903202 | 0.76 | HSD11B1 (0.45) | RAB9AKMT2ASMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL6875352 | 0.76 | PTGS2 (0.37) | KMT2AMEN1 | |
| SCHEMBL4903678 | 0.75 | HSD11B1 (0.44) | RAB9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6880057 | 0.75 | GAA (0.43) | KMT2AHPGDSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824954-B2 | DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS | JSR CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030113660-A1 | Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same | JSR CORPORATION (JP) | 2003-06-19 | — | — | US | disclosed |