SCHEMBL4900892

SCHEMBL4900892

Cc1ccc(S(=O)(=O)ON=C(c2ccccc2)C(F)(F)S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPT P10636 5/20 0.41
ALDH1A1 P00352 10/20 0.40
LMNA P02545 4/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 3/20 0.37
XBP1 P17861 3/20 0.37
MPI P34949 3/20 0.37
NPSR1 Q6W5P4 3/20 0.37
HSP90AA1 P07900 2/20 0.37
MAPK1 P28482 2/20 0.37
POLB P06746 1/20 0.37
TP53 P04637 1/20 0.36
VDR P11473 1/20 0.36
HSD11B1 P28845 1/20 0.36
PKM P14618 2/20 0.36
HTT P42858 2/20 0.36
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4903495 0.91 ALDH1A1 (0.44) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL16063707 0.88 LMNA (0.42) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL547034 0.85 MAPT (0.44) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL547035 0.85 MAPT (0.44) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL4891641 0.82 KMT2A (0.35) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL4897641 0.81 KMT2A (0.36) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL4899581 0.81 KMT2A (0.37) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL4903378 0.81 KMT2A (0.38) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL4902695 0.80 PSIP1 (0.35) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL6876264 0.79 RAB9A (0.36) KMT2AMEN1KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed