Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.41 |
| ▸ | ITGAV | P06756 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687895 | 0.82 | PTGER3 (0.35) | ITGB3ITGAVKMT2AMEN1 | |
| SCHEMBL687727 | 0.82 | POLB (0.44) | ITGB3ITGA2BITGAVRAB9A | |
| SCHEMBL687571 | 0.80 | ALDH1A1 (0.50) | ITGB3ITGA2BITGAVKMT2AMEN1 | |
| SCHEMBL687832 | 0.80 | PTGER3 (0.41) | KMT2AMEN1 | |
| SCHEMBL687749 | 0.80 | GAA (0.48) | ITGB3ITGA2BITGAVRAB9AGAA | |
| SCHEMBL688384 | 0.80 | KDM4E (0.42) | KMT2AMEN1 | |
| SCHEMBL687918 | 0.80 | KDM4E (0.44) | RAB9AKMT2AMEN1 | |
| SCHEMBL687837 | 0.79 | MAPT (0.37) | RAB9AKMT2AMEN1 | |
| SCHEMBL4757908 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2BITGAVGAAITGB5 | |
| SCHEMBL688104 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BITGAVRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1176956-B1 | CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |