Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758666 | 0.79 | HTT (0.68) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL4435358 | 0.79 | KMT2A (0.54) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8063391 | 0.73 | HSD11B1 (0.42) | HSD11B1HSD11B2 | |
| SCHEMBL6879513 | 0.73 | HSD11B1 (0.42) | HSD11B1HSD11B2 | |
| SCHEMBL8060470 | 0.73 | HSD11B1 (0.42) | HSD11B1HSD11B2 | |
| SCHEMBL10820607 | 0.70 | POLB (0.44) | ALDH1A1HSD11B1SMN1; SMN2HSD11B2 | |
| SCHEMBL12849249 | 0.66 | CCR2 (0.75) | KDM4EALDH1A1 | |
| SCHEMBL14398955 | 0.66 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL14398974 | 0.65 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6876735 | 0.65 | EPHX2 (0.35) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |