Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388697 | 0.86 | ALDH1A1 (0.52) | METAP2ALDH1A1MEN1USP2KMT2A | |
| SCHEMBL3692519 | 0.84 | NPSR1 (0.50) | NPSR1ALDH1A1POLBPPARGPPARD | |
| SCHEMBL14093023 | 0.83 | ALDH1A1 (0.46) | NPSR1METAP2ALDH1A1MEN1USP2 | |
| SCHEMBL6883303 | 0.77 | HSD17B10 (0.51) | NPSR1POLBHPGD | |
| SCHEMBL1287171 | 0.76 | ALDH1A1 (0.54) | METAP2ALDH1A1MEN1USP2KMT2A | |
| SCHEMBL4814721 | 0.76 | APEX1 (0.55) | NPSR1ALDH1A1POLBMAPTHPGD | |
| SCHEMBL672247 | 0.76 | NPSR1 (0.56) | NPSR1ALDH1A1POLBHPGD | |
| SCHEMBL6882571 | 0.75 | POLB (0.69) | ALDH1A1POLBHPGDPPARGPPARD | |
| SCHEMBL3668067 | 0.75 | FFAR1 (0.52) | NPSR1ALDH1A1 | |
| SCHEMBL6686883 | 0.75 | METAP2 (0.44) | METAP2ALDH1A1MEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102432494-B | Novel chemical total synthesis preparation method for coronalon | SOUTH CHINA BOTAN GARDEN CAS | 2013-12-04 | — | — | CN | claimed |
| CN-102432494-A | Novel chemical total synthesis preparation method of Coronalon | SOUTH CHINA BOTAN GARDEN CAS | 2012-05-02 | — | — | CN | claimed |
| CN-102432494-B | Novel chemical total synthesis preparation method for coronalon | SOUTH CHINA BOTAN GARDEN CAS | 2013-12-04 | — | — | CN | disclosed |
| CN-102432494-B | Novel chemical total synthesis preparation method for coronalon | SOUTH CHINA BOTAN GARDEN CAS | 2013-12-04 | — | — | CN | disclosed |
| CN-102432494-A | Novel chemical total synthesis preparation method of Coronalon | SOUTH CHINA BOTAN GARDEN CAS | 2012-05-02 | — | — | CN | disclosed |
| CN-102432494-A | Novel chemical total synthesis preparation method of Coronalon | SOUTH CHINA BOTAN GARDEN CAS | 2012-05-02 | — | — | CN | disclosed |
| US-20040087655-A1 | 6-Substituted indanoyl amino acid conjugates as mimics to the biological activity of coronatine | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV (DE) | 2004-05-06 | — | — | US | disclosed |
| EP-1351922-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055480-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | MAX PLANCK GESELLSCHAFT (DE) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087655-A1 | 6-Substituted indanoyl amino acid conjugates as mimics to the biological activity of coronatine | CORO1C, CORO1A, AGER | NPSR1 3296/4885METAP2 741/4885ALDH1A1 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.