Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16429034 | 0.88 | IDO1 (0.41) | KMT2AL3MBTL1LMNACYP1A2CYP2C19 | |
| SCHEMBL6881619 | 0.87 | TRPV1 (0.40) | LMNACYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL6884492 | 0.84 | BCHE (0.43) | KMT2AL3MBTL1LMNACYP1A2CYP2C19 | |
| SCHEMBL9781489 | 0.82 | THRA (0.40) | — | |
| SCHEMBL26191458 | 0.82 | KMT2A (0.39) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL10473352 | 0.81 | LMNA (0.51) | KMT2AL3MBTL1LMNACYP1A2CYP2C19 | |
| SCHEMBL16429035 | 0.78 | IDO1 (0.43) | L3MBTL1IDO1 | |
| SCHEMBL4597977 | 0.78 | OPRD1 (0.39) | — | |
| SCHEMBL6872361 | 0.77 | LMNA (0.42) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6855933 | 0.77 | L3MBTL1 (0.41) | KMT2AL3MBTL1LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357258-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-12-26 | — | — | CN | claimed |
| CN-1170812-C | Method for synthesizing diphenyl-keto-acid derivative | 上海麦普化工有限公司 | 2004-10-13 | — | — | CN | claimed |
| CN-1354168-A | Method for synthesizing diphenyl-keto-acid derivative | SHANGHAI MAIPU CHEMICAL INDUST (CN) | 2002-06-19 | — | — | CN | claimed |
| EP-0853079-B1 | Production of keto acids | CIBA SC HOLDING AG (CH) | 2002-06-05 | — | — | EP | claimed |
| US-5925787-A | Production of keto acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-07-20 | — | — | US | claimed |
| CN-1197062-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 1998-10-28 | — | — | CN | claimed |
| EP-0853079-A1 | Production of keto acids | Ciba SC Holding AG (CH) | 1998-07-15 | — | — | EP | claimed |
| CN-100357258-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-12-26 | — | — | CN | disclosed |
| CN-1301962-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-02-28 | — | — | CN | disclosed |
| CN-1575274-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 2005-02-02 | — | — | CN | disclosed |
| US-20040242891-A1 | Production of keto acids | CAMPBELL JONATHAN (GB) | 2004-12-02 | — | — | US | disclosed |
| CN-1170812-C | Method for synthesizing diphenyl-keto-acid derivative | 上海麦普化工有限公司 | 2004-10-13 | — | — | CN | disclosed |
| US-6635602-B1 | Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-21 | — | — | US | disclosed |
| EP-1107972-A1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | Ciba SC Holding AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000026037-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000012318-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012513-A1 | NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| US-5925787-A | Production of keto acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-07-20 | — | — | US | disclosed |
| CN-1197062-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 1998-10-28 | — | — | CN | disclosed |
| EP-0853079-A1 | Production of keto acids | Ciba SC Holding AG (CH) | 1998-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242891-A1 | Production of keto acids | PKLR, KHK, ME1 | KMT2A 552/4885L3MBTL1 1776/4885LMNA 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.