Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893793 | 0.83 | CYP3A4 (0.33) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL6895217 | 0.83 | SIGMAR1 (0.40) | CYP2D6IDO1TDO2LMNAKDM4E | |
| SCHEMBL6893114 | 0.81 | SIGMAR1 (0.42) | SLC6A2SLC6A4SLC6A3ANPEPKDM4E | |
| SCHEMBL6892044 | 0.80 | LMNA (0.38) | GBA1CYP2D6IDO1TDO2ADRA2A | |
| SCHEMBL6887515 | 0.79 | CES2 (0.32) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL6887215 | 0.78 | MAOB (0.41) | IDO1ANPEP | |
| SCHEMBL6894924 | 0.77 | KDM4E (0.43) | AOC3ANPEPADRA2AADRA2CLMNA | |
| SCHEMBL6895263 | 0.77 | KDM4E (0.43) | AOC3CYP2D6ANPEPADRA2AADRA2C | |
| SCHEMBL6895046 | 0.76 | IDO1 (0.33) | IDO1 | |
| SCHEMBL5578711 | 0.76 | BACE1 (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |