Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887215 | 0.89 | MAOB (0.41) | IDO1MAOBMAOASCN9ACTSD | |
| SCHEMBL6892044 | 0.89 | LMNA (0.38) | IDO1CTSDBACE1 | |
| SCHEMBL6895217 | 0.89 | SIGMAR1 (0.40) | IDO1MAOBMAOASCN9A | |
| SCHEMBL6891167 | 0.88 | TACR1 (0.36) | — | |
| SCHEMBL6887515 | 0.84 | CES2 (0.32) | ADRB1CES2CES1 | |
| SCHEMBL5578711 | 0.84 | BACE1 (0.35) | MAOBMAOASCN9ACTSDBACE1 | |
| SCHEMBL6888146 | 0.84 | GBA1 (0.34) | MAOBMAOA | |
| SCHEMBL6889713 | 0.83 | MEN1 (0.40) | IDO1CTSDBACE1 | |
| SCHEMBL6893793 | 0.83 | CYP3A4 (0.33) | ADRB1CES2CES1 | |
| SCHEMBL6894740 | 0.81 | TAAR1 (0.46) | IDO1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |