Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3300526 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL4797926 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL7069645 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL93647 | 0.75 | — | — | |
| Fluoride Ion SCHEMBL27280150 | 0.75 | — | — | |
| Potassium Ion SCHEMBL25364189 | 0.71 | — | — | |
| Fluoride Ion SCHEMBL1943306 | 0.71 | — | — | |
| Water SCHEMBL509801 | 0.71 | — | — | |
| Fluoride Ion SCHEMBL601529 | 0.71 | — | — | |
| Fluoride Ion SCHEMBL6175 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118872-A1 | INSULATIVE POLYURETHANE RIDGID FOAM BASED ON TDI LIQUID RESIDUE | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| WO-2016162255-A1 | INSULATIVE POLYURETHANE RIGID FOAM BASED ON TDI LIQUID RESIDUE | BASF SE (DE) | 2016-10-13 | — | — | WO | disclosed |
| US-6825277-B2 | THERMOPLASTIC ELASTOMER, VULCANIZED RUBBER, AND POLYOLEFIN; POLAR MODIFIER MIXTURE OF CHLORINATED POLYOLEFIN RESIN AND POLYURETHANE; TEAR STRENGTH, MECHANICAL PROPERTIES, STABILITY | ADVANCED ELASTOMER SYSTEMS, L.P. | 2004-11-30 | — | — | US | disclosed |
| US-20040077791-A1 | Maintains elasticity | ADVANCED ELASTOMER SYSTEMS, L.P. | 2004-04-22 | — | — | US | disclosed |
| US-5457146-A | Impact strength, heat resistance, ignition resistance | THE DOW CHEMICAL COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0374932-B1 | Rigid foams prepared from treated toluene diisocyanate residue | DOW CHEMICAL CO (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5216042-A | Purging with solvent and/or gas to remove chloride containing vapors; polyurethanes; polyureas; rigid foams | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0418367-A4 | SOLVENT RESISTANT POLYETHERPOLYURETHANE PRODUCTS AND PROCESS FOR PREPARING THE SAME | — | 1991-10-23 | — | — | EP | disclosed |
| EP-0418367-A1 | SOLVENT RESISTANT POLYETHERPOLYURETHANE PRODUCTS AND PROCESS FOR PREPARING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |
| US-5001167-A | Solvent resistant polyetherpolyurethane products | THE DOW CHEMICAL COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| WO-1990011310-A1 | SOLVENT RESISTANT POLYETHERPOLYURETHANE PRODUCTS AND PROCESS FOR PREPARING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |
| EP-0374932-A1 | Rigid foams prepared from treated toluene diisocyanate residue | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |
| US-4904704-A | REACTING HYDROLYZABLE CHLORIDE WITH EPOXY COMPONENT; POLYISOCYANURATES AND POLYURETHANES | THE DOW CHEMICAL COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4758603-A | Dithiocarbamate internal mold release agents | THE DOW CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | disclosed |