Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894740 | 0.88 | TAAR1 (0.46) | ALDH1A1ADRB2MEN1KMT2ACASR | |
| SCHEMBL6895046 | 0.88 | IDO1 (0.33) | — | |
| SCHEMBL6895217 | 0.81 | SIGMAR1 (0.40) | ALDH1A1ADRB2MEN1KMT2ACASR | |
| SCHEMBL6894401 | 0.80 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL6887215 | 0.79 | MAOB (0.41) | — | |
| SCHEMBL6892044 | 0.78 | LMNA (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6887515 | 0.77 | CES2 (0.32) | ADRB2 | |
| SCHEMBL6888146 | 0.77 | GBA1 (0.34) | ALDH1A1TSHRKMT2A | |
| SCHEMBL5578711 | 0.77 | BACE1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6889713 | 0.76 | MEN1 (0.40) | MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |