Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 5/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894401 | 0.90 | MEN1 (0.39) | BACE1MEN1KMT2A | |
| SCHEMBL6891167 | 0.88 | TACR1 (0.36) | TAAR1CASRADRB2ALDH1A1MEN1 | |
| SCHEMBL165645 | 0.87 | CASR (0.57) | TAAR1CASRMEN1KMT2A | |
| SCHEMBL4692485 | 0.87 | CASR (0.57) | TAAR1CASRMEN1KMT2A | |
| SCHEMBL6887215 | 0.87 | MAOB (0.41) | BACE1IDO1AGXT | |
| SCHEMBL5578711 | 0.85 | BACE1 (0.35) | BACE1ALDH1A1MEN1KMT2A | |
| SCHEMBL6895217 | 0.84 | SIGMAR1 (0.40) | CASRADRB2IDO1ALDH1A1LMNA | |
| SCHEMBL6889713 | 0.84 | MEN1 (0.40) | TAAR1BACE1IDO1AGXTMEN1 | |
| SCHEMBL6895816 | 0.82 | HTR2A (0.48) | CASRIDO1LMNA | |
| SCHEMBL6895046 | 0.81 | IDO1 (0.33) | BACE1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |