Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578847 | 1.00 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL1318953 | 1.00 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL24164093 | 1.00 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8010970 | 0.82 | RIPK1 (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8907610 | 0.80 | RIPK1 (0.53) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3096537 | 0.80 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3096547 | 0.80 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3081755 | 0.80 | RIPK1 (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL12213295 | 0.80 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL75867 | 0.80 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102517342-A | Method for catalytic synthesis of R-2-bromo-1-aryl alcohol using carrot root whole cells | UNIV JIANGNAN | 2012-06-27 | — | — | CN | claimed |
| CN-114560892-A | Chiral tridentate nitrogen phosphine ligand synthesized based on ferrocene skeleton and application thereof | 广东工业大学 | 2022-05-31 | — | — | CN | disclosed |
| US-10309035-B2 | Method of preparing sample for crystal structure analysis, method of determining absolute configuration of chiral compound, and polynuclear metal complex monocrystal | THE UNIVERSITY OF TOKYO (JP) | 2019-06-04 | — | — | US | disclosed |
| US-10309035-B2 | Method of preparing sample for crystal structure analysis, method of determining absolute configuration of chiral compound, and polynuclear metal complex monocrystal | THE UNIVERSITY OF TOKYO (JP) | 2019-06-04 | — | — | US | disclosed |
| EP-3118610-B1 | METHOD OF PREPARING SAMPLE FOR CRYSTAL STRUCTURE ANALYSIS, METHOD OF DETERMINING ABSOLUTE CONFIGURATION OF CHIRAL COMPOUND, AND POLYNUCLEAR METAL COMPLEX MONOCRYSTAL | UNIV TOKYO (JP) | 2018-06-06 | — | — | EP | disclosed |
| US-20170016138-A1 | METHOD OF PREPARING SAMPLE FOR CRYSTAL STRUCTURE ANALYSIS, METHOD OF DETERMINING ABSOLUTE CONFIGURATION OF CHIRAL COMPOUND, AND POLYNUCLEAR METAL COMPLEX MONOCRYSTAL | THE UNIVERSITY OF TOKYO (JP) | 2017-01-19 | — | — | US | disclosed |
| US-20170016138-A1 | METHOD OF PREPARING SAMPLE FOR CRYSTAL STRUCTURE ANALYSIS, METHOD OF DETERMINING ABSOLUTE CONFIGURATION OF CHIRAL COMPOUND, AND POLYNUCLEAR METAL COMPLEX MONOCRYSTAL | THE UNIVERSITY OF TOKYO (JP) | 2017-01-19 | — | — | US | disclosed |
| US-20170016138-A1 | METHOD OF PREPARING SAMPLE FOR CRYSTAL STRUCTURE ANALYSIS, METHOD OF DETERMINING ABSOLUTE CONFIGURATION OF CHIRAL COMPOUND, AND POLYNUCLEAR METAL COMPLEX MONOCRYSTAL | THE UNIVERSITY OF TOKYO (JP) | 2017-01-19 | — | — | US | disclosed |
| EP-3118610-A1 | METHOD OF PREPARING SAMPLE FOR CRYSTAL STRUCTURE ANALYSIS, METHOD OF DETERMINING ABSOLUTE CONFIGURATION OF CHIRAL COMPOUND, AND POLYNUCLEAR METAL COMPLEX MONOCRYSTAL | The University of Tokyo (JP) | 2017-01-18 | — | — | EP | disclosed |
| CN-102517342-A | Method for catalytic synthesis of R-2-bromo-1-aryl alcohol using carrot root whole cells | UNIV JIANGNAN | 2012-06-27 | — | — | CN | disclosed |
| EP-1317461-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6509472-B2 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2003-01-21 | — | — | US | disclosed |
| US-20020038053-A1 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2002-03-28 | — | — | US | disclosed |
| WO-2002022623-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |
| US-6156940-A | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0713848-B1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5831132-A | REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS | SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0713848-A1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1996-05-29 | — | — | EP | disclosed |
| EP-0198440-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-HALO-1-PHENYL ETHANOL | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-26 | — | — | EP | disclosed |
| US-4857468-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038053-A1 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | ADH5, ADH1A, ADH1C | LMNA 2990/4885KDM4E 3167/4885L3MBTL1 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.