Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711392 | 0.89 | SMN1; SMN2 (0.43) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6779213 | 0.86 | KMT2A (0.49) | KMT2AALDH1A1QPCTMAPTHTT | |
| SCHEMBL6779342 | 0.83 | TP53 (0.51) | TP53KMT2AMEN1ALDH1A1QPCT | |
| SCHEMBL6772103 | 0.80 | MCHR1 (0.51) | TP53KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6777509 | 0.80 | FAAH (0.47) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6776681 | 0.78 | QPCT (0.55) | KMT2AALDH1A1QPCTMAPT | |
| SCHEMBL6773196 | 0.78 | ALDH1A1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL6777932 | 0.77 | MAPT (0.43) | TP53KMT2AQPCTCYP2D6MAPT | |
| SCHEMBL13613835 | 0.77 | KMT2A (0.46) | TP53KMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6098139 | 0.77 | DYRK1A (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |