Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778719 | 0.85 | KMT2A (0.48) | ALDH1A1KMT2AMAPTHTTNPC1 | |
| SCHEMBL6891296 | 0.83 | TP53 (0.50) | TP53ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL6768544 | 0.81 | NPC1 (0.49) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6782875 | 0.80 | MAPT (0.47) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6779684 | 0.80 | MCHR1 (0.50) | TP53ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL6772950 | 0.79 | FAAH (0.53) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL6776616 | 0.78 | QPCT (0.52) | ALDH1A1KMT2AMAPTQPCT | |
| SCHEMBL6775775 | 0.76 | EPHX1 (0.37) | ALDH1A1KMT2ACYP3A4MAPT | |
| SCHEMBL6778012 | 0.75 | CCR3 (0.45) | TP53ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL6094589 | 0.75 | DYRK1A (0.37) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |