Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048877 | 0.82 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7048882 | 0.82 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7693611 | 0.82 | KDM4E (0.41) | KDM4E | |
| SCHEMBL11608418 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1MAPTMAOA | |
| SCHEMBL11608411 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1MAPTMAOA | |
| SCHEMBL11608423 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1MAPTMAOA | |
| SCHEMBL6579318 | 0.78 | NLRP3 (0.52) | CYP2C19NPSR1MAPTMEN1KMT2A | |
| SCHEMBL9443446 | 0.77 | CYP1A2 (0.46) | CYP1A2CYP2C19NPSR1MAPTMAOA | |
| SCHEMBL9876495 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11394655 | 0.76 | ALOX5 (0.45) | CA12CA9SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677371-B1 | ANTIARRHYTHMIA AGENTS SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-4-(2-PHENYLETHOXY)-2H-1-BENZOPYRAN-3 -OL, USED FOR PROPHYLAXIS OF CARDIOVASCULAR DISORDERS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-5162553-A | Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5066816-A | PROCESSES FOR PREPARING OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUNDS AND INTERMEDIATES THEREFOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0386640-A2 | Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4110347-A | ANTIHYPERTENSIVE | BEECHAM GROUP LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |