SCHEMBL6892374

SCHEMBL6892374

COCCOCOC(C)Cc1ccc(C(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 12/20 0.51
TSHR P16473 2/20 0.43
CASP6 P55212 1/20 0.43
PDK1 Q15118 1/20 0.41
LMNA P02545 1/20 0.40
MYC P01106 1/20 0.39
MAX P61244 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889362 0.87 ALDH1A1 (0.39) HCAR3PDK1LMNA
SCHEMBL17511817 0.81 HCAR3 (0.58) HCAR3TSHRCASP6LMNA
SCHEMBL6892370 0.77 HCAR3 (0.55) HCAR3TSHRCASP6PDK1LMNA
SCHEMBL29886944 0.77 HCAR3 (0.55) HCAR3TSHRCASP6PDK1LMNA
SCHEMBL16129649 0.75 HCAR3 (0.56) HCAR3TSHRCASP6LMNA
SCHEMBL4175596 0.74 CASP6 (0.58) HCAR3TSHRCASP6LMNA
SCHEMBL28748754 0.72 HCAR3 (0.51) HCAR3TSHRCASP6PDK1LMNA
SCHEMBL2366810 0.71 HCAR3 (0.61) HCAR3TSHRCASP6LMNA
SCHEMBL20757 0.71 PDK1 (0.68) HCAR3TSHRCASP6PDK1LMNA
SCHEMBL6707224 0.71 MYC (0.55) HCAR3TSHRCASP6LMNAMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004089529-A1 METHOD FOR THE INTRAMOLECULAR ENERGY TRANSFER FOR THE CLEAVAGE OF LABILE FUNCTIONAL GROUP FROM BIOMOLECULES AND THE PROTECTED BIOMOLECULES Universität Konstanz (DE) 2004-10-21 WO disclosed