SCHEMBL6892583

SCHEMBL6892583

CCOC(=O)Oc1c(C)cc(C)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
NLRP3 Q96P20 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
SOAT1 P35610 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CUL4A Q13619 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.40
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050553 0.86 CYP3A4 (0.49) ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19
SCHEMBL15509359 0.85 RAPGEF4 (0.40) ALDH1A1KMT2AMEN1KDM4EMAPT
SCHEMBL18050456 0.84 NLRP3 (0.42) ALDH1A1NLRP3SMN1; SMN2CYP1A2CYP3A4
SCHEMBL6894114 0.83 MAPT (0.44) ALDH1A1NLRP3SMN1; SMN2SOAT1CYP1A2
SCHEMBL14363151 0.82 CUL4A (0.44) ALDH1A1SOAT1CUL4AKMT2AMEN1
SCHEMBL10958003 0.81 RAPGEF4 (0.37) ALDH1A1SMN1; SMN2L3MBTL1KMT2AMEN1
SCHEMBL19543205 0.81 CUL4A (0.52) ALDH1A1SMN1; SMN2SOAT1CUL4AKMT2A
SCHEMBL19543215 0.81 ALDH1A1 (0.43) ALDH1A1NLRP3SMN1; SMN2SOAT1CYP1A2
SCHEMBL6894278 0.80 L3MBTL1 (0.51) ALDH1A1NLRP3SMN1; SMN2SOAT1CYP1A2
SCHEMBL9682715 0.79 RAPGEF4 (0.41) ALDH1A1KMT2AMEN1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109937197-B Electrochemical process for preparing aryl alkyl carbonates and diaryl carbonates 科思创德国股份有限公司 2022-05-03 CN disclosed
EP-3541778-B1 ELECTROCHEMICAL METHOD FOR THE PRODUCTION OF ARYLALKYLCARBONATES AND DIARYL CARBONATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-05-19 EP disclosed
EP-3541778-A1 ELECTROCHEMICAL METHOD FOR PRODUCING ARYL ALKYL CARBONATES AND DIARYL CARBONATES Covestro Deutschland AG (DE) 2019-09-25 EP disclosed
WO-2018091370-A1 ELECTROCHEMICAL METHOD FOR PRODUCING ARYL ALKYL CARBONATES AND DIARYL CARBONATES COVESTRO DEUTSCHLAND AG (DE) 2018-05-24 WO disclosed
EP-3321250-A1 ELECTROCHEMICAL METHOD FOR THE PRODUCTION OF ARYLALKYLCARBONATES AND DIARYL CARBONATES Covestro Deutschland AG (DE) 2018-05-16 EP disclosed
US-6677331-B2 HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS MEIJI SEIKA KAISHA, LTD. (JP) 2004-01-13 US disclosed
US-20030149016-A1 Novel carbapenem derivatives KANO YUKO (JP) 2003-08-07 US disclosed
EP-1101766-A1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149016-A1 Novel carbapenem derivatives DPEP1, TMPRSS15, STK35 ALDH1A1 1161/4885NLRP3 1052/4885SMN1; SMN2 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.