Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.46 |
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28933188 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL28933170 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL29461363 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL5275683 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL28933174 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL23093987 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL5273170 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL5965054 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL1066590 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL28933175 | 1.00 | SMPD1 (0.46) | SMPD1FDPSTSHRTHRBDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174849-B1 | SYNTHESIS OF PYRROLIDINE DERIVATIVES | UNIV TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2019-03-13 | — | — | EP | claimed |
| EP-0886551-B1 | STABILITY CONTROL AGENT COMPOSITION FOR POLYOLEFIN FOAM | KNAUS DENNIS A (US) | 2004-08-04 | — | — | EP | claimed |
| EP-3174849-B1 | SYNTHESIS OF PYRROLIDINE DERIVATIVES | UNIV TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2019-03-13 | — | — | EP | disclosed |
| EP-3174849-A1 | PRODUCTION OF PYRROLIDINE DERIVATIVES | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2017-06-07 | — | — | EP | disclosed |
| EP-3174390-A1 | COMPOSITION FOR MODULATING THE ACTIVITY OF NON-STRUCTURAL PROTEINS | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2017-06-07 | — | — | EP | disclosed |
| US-20170137378-A1 | Production of Pyrrolidine Derivatives | LICIT SOLUTIONS GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170137379-A1 | Composition for the Modulation of the Activity of Non-Structure Proteins | LICIT SOLUTIONS GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| WO-2016016168-A1 | COMPOSITION FOR MODULATING THE ACTIVITY OF NON-STRUCTURAL PROTEINS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2016-02-04 | — | — | WO | disclosed |
| WO-2016016167-A1 | PRODUCTION OF PYRROLIDINE DERIVATIVES | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2016-02-04 | — | — | WO | disclosed |
| EP-1017668-B1 | METHOD FOR PRODUCING GLUCOPROTAMINES | COGNIS DEUTSCHLAND GMBH (DE) | 2003-03-19 | — | — | EP | disclosed |
| EP-1017668-A1 | METHOD FOR PRODUCING GLUCOPROTAMINES | Cognis Deutschland GmbH (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015496-A1 | METHOD FOR PRODUCING GLUCOPROTAMINES | COGNIS DEUTSCHLAND GMBH (DE) | 1999-04-01 | — | — | WO | disclosed |
| EP-0156275-B1 | ANTIMICROBIALLY ACTIVE SUBSTANCES, THEIR PREPARATION AND THEIR USE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-06-07 | — | — | EP | disclosed |
| EP-0156275-A2 | Antimicrobially active substances, their preparation and their use | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-10-02 | — | — | EP | disclosed |
| WO-1984004919-A1 | N-SUBSTITUTED ALKYLAMINES, PREPARATION THEREOF AND UTILIZATION THEREOF AS ANTIMICROBIAL AGENTS | HENKEL KGAA (DE) | 1984-12-20 | — | — | WO | disclosed |
| US-4169074-A | Compositions for cold water washing containing N-substituted ω-hydroxyalkane carboxylic acid amides | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137379-A1 | Composition for the Modulation of the Activity of Non-Structure Proteins | PEBP1, TUFM, HSPBP1 | SMPD1 1670/4885FDPS 510/4885TSHR 4632/4885 |
| US-20170137378-A1 | Production of Pyrrolidine Derivatives | PPOX, DHPS, ALDH18A1 | SMPD1 2156/4885FDPS 11/4885TSHR 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.