SCHEMBL6899802

SCHEMBL6899802

C#CC(C)(C)O[SiH2]C(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
RIPK1 Q13546 2/20 0.31
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707823 0.79 SLC6A4 (0.37) RIPK1ATML3MBTL1
SCHEMBL704150 0.68 KMT2A (0.40) THRBL3MBTL1
SCHEMBL27692043 0.68 RIPK1 (0.39) RIPK1
SCHEMBL433140 0.67 DPP4 (0.39)
SCHEMBL705271 0.65 TAAR1 (0.37) L3MBTL1
SCHEMBL27657612 0.65 RIPK1 (0.36) THRBRIPK1
SCHEMBL18405594 0.65 CA4 (0.39) RIPK1ATML3MBTL1
SCHEMBL6251903 0.63 DPP4 (0.36)
SCHEMBL587674 0.63 DPP4 (0.36)
SCHEMBL242576 0.63 LMNA (0.40) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5708046-A ALKENYL SILOXANES, ORGANOHYDROGENSILOXANES, POLYMERIZATION INHIBITORS FOR STORAGE STABILITY DOW CORNING CORPORATION (US) 1998-01-13 US claimed
EP-0764703-A2 Silicone release coating compositions Dow Corning Toray Silicone Company Ltd. (JP) 1997-03-26 EP claimed
US-6677407-B1 LOW TEMPERATURE, QUICK SETTING SILICONE RELEASE AGENTS COMPRISING MIXTURES OF POLYSILOXANES, ORGANOSILICON COMPOUNDS, KARSTEDT CATALYSTS AND DILUENTS, USED AS ADHESIVE TAPES OR LABELS DOW CORNING CORPORATION 2004-01-13 US disclosed
EP-0826732-A2 Silicone release coating compositions DOW CORNING CORPORATION (US) 1998-03-04 EP disclosed
US-5708046-A ALKENYL SILOXANES, ORGANOHYDROGENSILOXANES, POLYMERIZATION INHIBITORS FOR STORAGE STABILITY DOW CORNING CORPORATION (US) 1998-01-13 US disclosed
EP-0764703-A2 Silicone release coating compositions Dow Corning Toray Silicone Company Ltd. (JP) 1997-03-26 EP disclosed