Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912567 | 0.94 | PPID (0.52) | L3MBTL1LMNAPPIDALDH1A1MAPK1 | |
| SCHEMBL18510019 | 0.93 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1MAPK1HSD17B10CYP1A2 | |
| SCHEMBL21959506 | 0.89 | LMNA (0.49) | L3MBTL1LMNAALDH1A1MAPK1PKM | |
| SCHEMBL381081 | 0.87 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL15902594 | 0.87 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL21959524 | 0.86 | L3MBTL1 (0.47) | L3MBTL1LMNAPPIDALDH1A1MAPK1 | |
| SCHEMBL20833056 | 0.86 | TSHR (0.50) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6902424 | 0.83 | POLB (0.51) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL10832272 | 0.83 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL23901996 | 0.82 | ALDH1A1 (0.51) | L3MBTL1PPIDALDH1A1MAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084794-B2 | Controlled cyclization of peptoids to form chiral diketopiperazines | TRIAD NATIONAL SECURITY, LLC (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200131140-A1 | CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES | TRIAD NATIONAL SECURITY, LLC (US) | 2020-04-30 | — | — | US | disclosed |
| WO-2011061271-A1 | SUBSTITUTED CARBAMOYLMETHYLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS | NOVARTIS AG (CH) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084794-B2 | Controlled cyclization of peptoids to form chiral diketopiperazines | NPPA, NPEPPS, RRP15 | L3MBTL1 4335/4885LMNA 2344/4885PPID 740/4885 |
| US-20200131140-A1 | CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES | NPPA, NPEPPS, RRP15 | L3MBTL1 4335/4885LMNA 2344/4885PPID 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.