SCHEMBL6903537

SCHEMBL6903537

OC1c2ccccc2-c2ccccc2C1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.46
HTR2A P28223 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
CYP2D6 P10635 2/20 0.44
POLB P06746 1/20 0.43
PARP3 Q9Y6F1 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CYP1A2 P05177 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469331 1.00 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL6903531 1.00 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL29503342 1.00 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL29469332 1.00 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
Alcohol SCHEMBL28567797 0.87 GPR3 (0.43) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL23005422 0.82 HTR2A (0.43) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL3994733 0.82 CYP2D6 (0.55) HDAC3HDAC4HDAC7HDAC8HDAC6
SCHEMBL8205238 0.82 ALDH1A1 (0.43) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL216862 0.81 MAOA (0.52) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL29376368 0.81 MAOA (0.52) GPR3HTR2AHDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112225885-B Copolyester and preparation method thereof 万华化学集团股份有限公司 2022-04-22 CN claimed
CN-112225885-A Copolyester and preparation method thereof 万华化学集团股份有限公司 2021-01-15 CN claimed
JP-6065131-A None JP disclosed
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed
CN-112225885-B Copolyester and preparation method thereof 万华化学集团股份有限公司 2022-04-22 CN disclosed
CN-112441920-B Method for copper photocatalytic synthesis of 9-acetoxyl-9, 10-dihydrophenanthrene compound 浙江工业大学 2022-03-18 CN disclosed
CN-112441921-B Method for synthesizing 9-acetoxyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis 浙江工业大学 2022-03-18 CN disclosed
CN-112441920-A Method for copper photocatalytic synthesis of 9-acetoxyl-9, 10-dihydrophenanthrene compound 浙江工业大学 2021-03-05 CN disclosed
CN-112441921-A Method for synthesizing 9-acetoxyl-9, 10-dihydrophenanthrene compound by virtue of iridium photocatalysis 浙江工业大学 2021-03-05 CN disclosed
CN-112225885-A Copolyester and preparation method thereof 万华化学集团股份有限公司 2021-01-15 CN disclosed
US-20150295244-A1 ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, AND POWER STORAGE DEVICE PANASONIC CORPORATION (JP) 2015-10-15 US disclosed
US-6168838-B1 FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2001-01-02 US disclosed
US-6018058-A SUCH AS PHENANTHRO(9,10-B)-P-DIOXIN SUBSTITUTED WITH AT LEAST ONE AROMATIC GROUP; IRRADIATING TO ACTIVATE REACTION FOR CLEAVING DNA UNIVERSITY OF CINCINNATI (US) 2000-01-25 US disclosed
EP-0946473-A1 FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES Aventis Research & Technologies GmbH & Co. KG. (DE) 1999-10-06 EP disclosed
WO-1998027035-A1 FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-06-25 WO disclosed
WO-1996020205-A1 1,4-DIHYDRODIOXINS AND RELATED COMPOUNDS AS DNA CLEAVING REAGENTS UNIVERSITY OF CINCINNATI (US) 1996-07-04 WO disclosed
JP-H0665131-A PRODUCTION OF 2,7-DIHYDROXY-9,10-DIHYDROPHENANTHRENE AGENCY OF IND SCIENCE & TECHNOL 1994-03-08 JP disclosed
EP-0071458-B1 PROCESS FOR PRODUCING ETHYLENE GLYCOL Redox Technologies Inc. (US) 1984-10-10 EP disclosed
US-4412085-A FROM METHANOL, FORMALDEHYDE, WATER, AND AN ORGANIC PEROXIDE REDOX TECHNOLOGIES INC A NJ CORP 1983-10-25 US disclosed
EP-0071458-A1 Process for producing ethylene glycol Redox Technologies Inc. (US) 1983-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 GPR3 4018/4885HTR2A 2808/4885HDAC3 2683/4885
US-20150295244-A1 ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, AND POWER STORAGE DEVICE NDUFV2, NDUFA2, SSBP1 GPR3 4620/4885HTR2A 3720/4885HDAC3 2632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.