Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27623239 | 0.80 | MAPT (0.46) | KMT2AALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL62940 | 0.80 | MAPT (0.46) | KMT2AALDH1A1MAPTHSD17B10NPC1 | |
| Alanine SCHEMBL6904183 | 0.78 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTHSD17B10HTT | |
| SCHEMBL27404604 | 0.71 | PTGS2 (0.39) | RETKDRALDH1A1MAPTHSD17B10 | |
| SCHEMBL9701179 | 0.66 | TDP2 (0.35) | KMT2AALDH1A1MAPTHSD17B10L3MBTL1 | |
| SCHEMBL9864475 | 0.65 | MAPT (0.38) | KMT2AALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL1421444 | 0.65 | CRBN (0.41) | KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL9640804 | 0.63 | TSHR (0.54) | KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11583227 | 0.62 | TOP2A (0.42) | ALDH1A1MAPT | |
| Edetol SCHEMBL28132161 | 0.62 | CES2 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623714-A | Novel polypeptides with an α-amylase-inhibiting action, a process for their preparation, their use and pharmaceutical products | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-18 | — | — | US | disclosed |