Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030240 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MAPTADORA2ASMARCA2SMARCA4 | |
| SCHEMBL11481819 | 0.71 | ADORA2A (0.39) | ALDH1A1MAPTADORA2ATDP1MEN1 | |
| SCHEMBL20902858 | 0.70 | HTR7 (0.43) | ALDH1A1ADORA2ASMARCA2SMARCA4PBRM1 | |
| SCHEMBL16708761 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBMEN1TP53 | |
| SCHEMBL6904744 | 0.67 | ADORA2A (0.41) | ALDH1A1HTTSMN1; SMN2MAPTADORA2A | |
| SCHEMBL9122030 | 0.64 | ADORA2A (0.43) | ALDH1A1SMN1; SMN2MAPTADORA2ACYP1A2 | |
| SCHEMBL7028632 | 0.63 | PBRM1 (0.41) | ALDH1A1SMN1; SMN2MAPTADORA2ARAB9A | |
| SCHEMBL125609 | 0.62 | NSD2 (0.55) | ALDH1A1HTTSMN1; SMN2MAPTADORA2A | |
| SCHEMBL8671883 | 0.61 | ADORA2A (0.57) | ALDH1A1HTTSMN1; SMN2MAPTADORA2A | |
| SCHEMBL29401197 | 0.61 | ADORA2A (0.57) | ALDH1A1SMN1; SMN2MAPTADORA2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | disclosed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | GPX4, GPX1, AGK | ALDH1A1 714/4885HTT 4862/4885SMN1; SMN2 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.