Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 7/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20902858 | 0.69 | HTR7 (0.43) | PBRM1ALDH1A1L3MBTL1MAOAADORA2A | |
| SCHEMBL6904744 | 0.69 | ADORA2A (0.41) | PBRM1ALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL12105727 | 0.66 | CYP1A1 (0.50) | ALDH1A1MAPK1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29280562 | 0.66 | ALDH1A1 (0.38) | ALDH1A1MAPTNPSR1MAPK1RAB9A | |
| SCHEMBL9122030 | 0.66 | ADORA2A (0.43) | PBRM1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11481819 | 0.64 | ADORA2A (0.39) | PBRM1ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL7030240 | 0.64 | ALDH1A1 (0.34) | PBRM1ALDH1A1MAPTKDM4EADORA2A | |
| SCHEMBL7029698 | 0.63 | ALDH1A1 (0.33) | PBRM1ALDH1A1MAPTNPSR1RAB9A | |
| SCHEMBL11809699 | 0.63 | RAB9A (0.46) | PBRM1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6905334 | 0.63 | CACNB4 (0.41) | PBRM1ALDH1A1NPSR1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | disclosed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | GPX4, GPX1, AGK | PBRM1 2478/4885FABP3 2924/4885FABP4 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.