Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150474 | 0.89 | ALDH1A1 (0.50) | CALM1TAAR1TP53ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL29262829 | 0.86 | ALDH1A1 (0.48) | KDM4ECYP3A4MAPTCALM1TAAR1 | |
| SCHEMBL5139750 | 0.79 | TP53 (0.50) | KDM4ECYP3A4MAPTCALM1TAAR1 | |
| Diphenylmethane SCHEMBL3943306 | 0.77 | CALM1 (0.80) | KDM4ECYP3A4MAPTCALM1TAAR1 | |
| Hydrochloric Acid SCHEMBL28058678 | 0.77 | TP53 (0.48) | KDM4ECYP3A4MAPTCALM1TP53 | |
| Dioxane SCHEMBL7176882 | 0.75 | LMNA (0.41) | KDM4ECALM1TP53SIGMAR1LMNA | |
| SCHEMBL8600509 | 0.75 | TP53 (0.46) | KDM4ECYP3A4MAPTCALM1TP53 | |
| Dimethylamine SCHEMBL9472310 | 0.75 | TAAR1 (0.67) | KDM4ECYP3A4MAPTCALM1TAAR1 | |
| SCHEMBL3955494 | 0.74 | TSHR (0.50) | CALM1TP53ALDH1A1HPGDALOX15 | |
| SCHEMBL8597739 | 0.73 | TAAR1 (0.41) | CALM1TAAR1TP53SIGMAR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438072-B1 | NOVEL ORGANOMETALLIC COMPOUNDS CONTAINING A METAL BELONGING TO THE SECOND COLUMN OF THE PERIODIC TABLE, AND METHOD FOR PREPARING SAME | MICHELIN & CIE (FR) | 2016-11-23 | — | — | EP | claimed |
| US-20120135857-A1 | NOVEL ORGANOMETALLIC COMPOUNDS CONTAINING A METAL BELONGING TO THE SECOND COLUMN OF THE PERIODIC TABLE, AND METHOD FOR PREPARING SAME | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2012-05-31 | — | — | US | claimed |
| US-9315590-B2 | Catalytic system for conjugated diene polymerisation, polymerisation method and functional polymer obtained | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-04-19 | — | — | US | disclosed |
| US-20130274407-A1 | CATALYTIC SYSTEM FOR CONJUGATED DIENE POLYMERISATION, POLYMERISATION METHOD AND FUNCTIONAL POLYMER OBTAINED | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2013-10-17 | — | — | US | disclosed |
| US-8507397-B2 | Organometallic compounds containing a metal belonging to the second column of the periodic table, and method for preparing same | CAMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2013-08-13 | — | — | US | disclosed |
| US-20120135857-A1 | NOVEL ORGANOMETALLIC COMPOUNDS CONTAINING A METAL BELONGING TO THE SECOND COLUMN OF THE PERIODIC TABLE, AND METHOD FOR PREPARING SAME | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2012-05-31 | — | — | US | disclosed |
| WO-2004074333-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATIONOF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135857-A1 | NOVEL ORGANOMETALLIC COMPOUNDS CONTAINING A METAL BELONGING TO THE SECOND COLUMN OF THE PERIODIC TABLE, AND METHOD FOR PREPARING SAME | AS3MT, SSB, RRM2B | KDM4E 607/4885CYP3A4 2152/4885MAPT 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.