Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 7/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.50 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906376 | 0.77 | CACNA1H (0.48) | CACNA1HCACNA1GCACNA1ICYP1A2CYP2C19 | |
| SCHEMBL2185201 | 0.72 | WNT3A (0.71) | WNT3ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13329837 | 0.69 | NLRP3 (0.57) | CACNA1HCACNA1GCACNA1INLRP3SMN1; SMN2 | |
| SCHEMBL22816202 | 0.69 | VNN1 (0.49) | NLRP3SMN1; SMN2MAPK8EPHX2MEN1 | |
| SCHEMBL3704082 | 0.69 | KCNQ3 (0.54) | CACNA1HCACNA1GCACNA1IWNT3ANLRP3 | |
| SCHEMBL23973280 | 0.69 | NLRP3 (0.52) | CACNA1HCACNA1GCACNA1IWNT3ANLRP3 | |
| SCHEMBL18553697 | 0.69 | IDO1 (0.56) | CACNA1HCACNA1GCACNA1IWNT3ANLRP3 | |
| SCHEMBL6913787 | 0.69 | NPC1 (0.55) | CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL23484591 | 0.69 | PPARA (0.50) | NLRP3EPHX2P2RY14PPARA | |
| SCHEMBL4288466 | 0.68 | SMN1; SMN2 (0.47) | CYP1A2CYP2C19SMN1; SMN2CSNK1DEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | NIHON NOHYAKU CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1319657-A1 | N-(4-PYRAZOLYL)AMIDE DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE OF THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | CBR3, CYP8B1, CBR1 | CACNA1H 1947/4885CACNA1G 2082/4885CACNA1I 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.