Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 15/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069562 | 0.77 | MAPK8 (0.47) | CACNA1HCACNA1GCACNA1IKDM4EMEN1 | |
| SCHEMBL6907015 | 0.77 | CACNA1H (0.52) | CACNA1HCYP1A2CYP2C19SMN1; SMN2CACNA1G | |
| SCHEMBL4288466 | 0.74 | SMN1; SMN2 (0.47) | CYP1A2CYP2C19SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6560595 | 0.74 | RORC (0.47) | CACNA1HCACNA1GCACNA1IKDM4EMEN1 | |
| SCHEMBL8988057 | 0.72 | MAPK10 (0.48) | CACNA1HSMN1; SMN2CACNA1GCACNA1IKDM4E | |
| SCHEMBL8490597 | 0.72 | RORC (0.44) | CYP1A2CYP2C19SMN1; SMN2LMNAPOLB | |
| SCHEMBL8667377 | 0.71 | CACNA1H (0.41) | CACNA1HCACNA1GCACNA1IKDM4EMEN1 | |
| SCHEMBL8413441 | 0.71 | NOD2 (0.44) | CACNA1HCACNA1GCACNA1IKDM4EMEN1 | |
| SCHEMBL11564197 | 0.70 | RAB9A (0.54) | CACNA1GKDM4EMEN1LMNAPOLB | |
| SCHEMBL8490600 | 0.69 | PARP15 (0.54) | CACNA1GKDM4EMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | NIHON NOHYAKU CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1319657-A1 | N-(4-PYRAZOLYL)AMIDE DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE OF THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | CBR3, CYP8B1, CBR1 | CACNA1H 1947/4885CYP1A2 140/4885CYP2C19 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.