Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861604 | 0.81 | GABRA1 (0.64) | SLC6A4SLC6A2POLQGABRA1GABRB2 | |
| SCHEMBL12831776 | 0.81 | SLC6A4 (0.50) | CYP2D6CYP3A4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1698715 | 0.80 | GABRA1 (0.54) | SLC6A4SLC6A2SLC6A3GABRA1GABRB2 | |
| SCHEMBL11625501 | 0.79 | SLC6A4 (0.43) | CYP2D6CYP3A4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19148413 | 0.76 | SLC6A2 (0.45) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19124497 | 0.76 | SLC6A2 (0.45) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL30313045 | 0.76 | MAOB (0.45) | SLC6A4SLC6A2POLQGABRA1GABRB2 | |
| SCHEMBL18305266 | 0.76 | IDO1 (0.40) | SLC6A4SLC6A2POLQGABRA1GABRB2 | |
| SCHEMBL9068633 | 0.75 | ALDH1A1 (0.52) | GABRA1GABRB2CYP2C19ALOX15MAPK1 | |
| SCHEMBL396017 | 0.73 | CA2 (0.55) | GABRA1GABRB2ALOX15KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | CYP2D6 233/4885CYP3A4 55/4885SLC6A4 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.