Sugi Predict

Sugi Predict / Compounds / SCHEMBL690853

SCHEMBL690853

SCHEMBL690853

CC(=O)c1ccc(Br)nc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KCNJ1 P48048 1/20 0.46
▸ HDAC1 Q13547 2/20 0.41
▸ HDAC6 Q9UBN7 2/20 0.41
▸ HPGD P15428 2/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ NNMT P40261 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ MAOB P27338 1/20 0.40
▸ P4HA1 P13674 2/20 0.39
▸ P4HTM Q9NXG6 2/20 0.39
▸ HSD17B1 P14061 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ GAA P10253 1/20 0.38
▸ MIF P14174 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ HCAR3 P49019 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29480657 1.00 KCNJ1 (0.46) KCNJ1HDAC1HDAC6HPGDL3MBTL1
SCHEMBL23500079 0.86 MAPT (0.53) HPGDL3MBTL1MAPTRAB9ALMNA
SCHEMBL5973043 0.82 RXFP1 (0.44) HDAC1HDAC6HPGDMAPTRAB9A
SCHEMBL38414 0.80 P4HA1 (0.61) HPGDMAPTP4HA1P4HTMMIF
SCHEMBL29751460 0.80 P4HA1 (0.61) HPGDMAPTP4HA1P4HTMMIF
SCHEMBL7312742 0.80 P4HA1 (0.40) HDAC1HDAC6HPGDNNMTP4HA1
SCHEMBL5700551 0.78 HDAC1 (0.33) HDAC1HDAC6NNMTKMT2AP4HA1
SCHEMBL13825404 0.78 KCNJ1 (0.46) KCNJ1HDAC1HDAC6HPGDL3MBTL1
SCHEMBL15375343 0.78 DGAT1 (0.34) HDAC1HDAC6NNMTKMT2AP4HA1
SCHEMBL22229965 0.78 NNMT (0.61) L3MBTL1NNMTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 610 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432149-A Acid-alkali-resistant explosion-proof printing ink and preparation method thereof 天津世宇电子股份有限公司 2025-02-14 — — CN claimed
CN-118684983-A Antibacterial PVC composite material and application thereof in anti-slip pad 广东广海大实业有限公司 2024-09-24 — — CN claimed
CN-115010656-B Preparation method of 5-acetyl-2-bromopyridine 苏州昊帆生物股份有限公司 2024-04-26 — — CN claimed
CN-115010656-A Preparation method of 5-acetyl-2-bromopyridine 苏州昊帆生物股份有限公司 2022-09-06 — — CN claimed
CN-110204548-A A kind of pyridazine with sterilizing effect and triazole drug molecule and its preparation method and application 河南科技大学第一附属医院 2019-09-06 — — CN claimed
US-20260125400-A1 TYK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 — — US disclosed
EP-4731216-A1 HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS Augustine Therapeutics (BE) 2026-04-29 — — EP disclosed
US-20260109684-A1 QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF NEW YORK UNIVERSITY (US) 2026-04-23 — — US disclosed
US-12606568-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-04-21 — — US disclosed
US-20260041671-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS INC (US) 2026-02-12 — — US disclosed
US-20260042747-A1 KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF ALIVEXIS, INC. (JP) 2026-02-12 — — US disclosed
US-12539292-B2 BRM targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-03 — — US disclosed
EP-0885194-A1 PYRIDYL-PHENYL- AND BENZYLETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND FOR CONTROLLING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 1998-12-23 — — EP disclosed
EP-0860428-A2 Sulphonamide derivatives ELI LILLY AND COMPANY (US) 1998-08-26 — — EP disclosed
WO-1998033496-A1 SULPHONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1998-08-06 — — WO disclosed
WO-1997030032-A1 PYRIDYL-PHENYL- AND BENZYLETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND FOR CONTROLLING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 1997-08-21 — — WO disclosed
EP-0555068-B1 Oxime derivatives as 5-lipoxygenase inhibitors ZENECA LTD (GB) 1996-04-10 — — EP disclosed
US-5482966-A LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS ZENECA LIMITED (GB) 1996-01-09 — — US disclosed
US-5332757-A Enzyme inhibitors ZENECA LIMITED (GB) 1994-07-26 — — US disclosed
EP-0555068-A1 Oxime derivatives as 5-lipoxygenase inhibitors ZENECA LIMITED (GB) 1993-08-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125400-A1 TYK2 DEGRADERS AND USES THEREOF TYK2, CSNK2A1, CSNK2A2 KCNJ1 2822/4885HDAC1 266/4885HDAC6 384/4885
US-12539292-B2 BRM targeting compounds and associated methods of use ADRM1, SUMO2, BAZ1A KCNJ1 4799/4885HDAC1 422/4885HDAC6 181/4885
US-20260109684-A1 QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF AGER, GLP1R, HMGB1 KCNJ1 3023/4885HDAC1 3976/4885HDAC6 3771/4885
US-20260041671-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ADRM1, VHL, BAZ1A KCNJ1 4685/4885HDAC1 653/4885HDAC6 666/4885
US-12606568-B2 SMARCA degraders and uses thereof SMARCA1, SMARCD1, SMARCC1 KCNJ1 4325/4885HDAC1 578/4885HDAC6 475/4885
US-20260042747-A1 KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF KIT, LTK, HRH3 KCNJ1 824/4885HDAC1 661/4885HDAC6 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.