SCHEMBL6909217

SCHEMBL6909217

C[Si](C)=[Zr](CS(=O)(=O)O)(CS(=O)(=O)O)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.33
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774282 0.79 HTR2A (0.38) HTR6HTR2AKDM4ELMNATP53
SCHEMBL4019116 0.78 HTR6 (0.30) HTR6
SCHEMBL7766829 0.75 SIGMAR1 (0.38) HTR6HTR2AKDM4ELMNATP53
SCHEMBL6857144 0.71 HTR2A (0.37) HTR6HTR2AKDM4ELMNATP53
SCHEMBL376490 0.69 HTR2A (0.36) HTR6HTR2AKDM4ELMNATP53
SCHEMBL6908310 0.69 HTR2A (0.36) HTR6HTR2AKDM4ELMNATP53
SCHEMBL1538971 0.68 HTR2A (0.35) HTR6HTR2AKDM4ELMNATP53
SCHEMBL6906177 0.67 HTR2A (0.34) HTR6HTR2AKDM4ELMNATP53
Trifluoromethanesulfonic Acid SCHEMBL6910539 0.67
Trifluoromethanesulfonic Acid SCHEMBL615610 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0783022-B2 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
EP-0783022-B1 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6063871-A SPECIFIC HIGH-DENSITY ETHYLENE POLYMER AND A SPECIFIC ETHYLENE POLYMER, IN WHICH AT LEAST ONE IS PREPARED USING A METALLOCENE CATALYST, AND THE DENSITY RATIO THEREBETWEEN EXCEEDS 1; MOLDABILITY, CRACK RESISTANCE, STRENGTH AND RIGIDITY MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) 2000-05-16 US disclosed
EP-0783022-A1 ETHYLENIC POLYMER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-09 EP disclosed