Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GNRHR | P30968 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | CLPP | Q16740 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337803 | 0.91 | KDM4E (0.54) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL2301114 | 0.91 | ACHE (0.56) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL6909368 | 0.89 | DRD2 (0.45) | KMT2AACHEGABRA1GABRA2DRD4 | |
| SCHEMBL2302414 | 0.88 | KMT2A (0.48) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL2342240 | 0.87 | MAPT (0.55) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL2302172 | 0.86 | REV1 (0.52) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL2345662 | 0.83 | DRD2 (0.54) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL2347647 | 0.83 | KDM4E (0.54) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL2344801 | 0.83 | GNRHR (0.57) | KMT2AGNRHRACHEGABRA1GABRA2 | |
| SCHEMBL6907625 | 0.83 | CLPP (0.42) | KMT2AGNRHRDRD4DRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101804-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |