SCHEMBL6909662

SCHEMBL6909662

[Li]C1=C(N(C)C)c2ccccc2C1[Si](C)(C)NC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909960 0.87 LMNA (0.31)
SCHEMBL6908346 0.79 ALDH1A1 (0.31)
SCHEMBL7510367 0.78 GPR3 (0.36) GPR3
SCHEMBL540904 0.77 GPR3 (0.35) GPR3
Hydrochloric Acid SCHEMBL995806 0.76 GPR3 (0.34) GPR3
Hydrochloric Acid SCHEMBL6858048 0.76 GPR3 (0.34) GPR3
Hydrochloric Acid SCHEMBL6862745 0.76 GPR3 (0.34) GPR3
SCHEMBL6906509 0.75
SCHEMBL28790426 0.74 GPR3 (0.33) GPR3
SCHEMBL6910553 0.74 APAF1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923589-B1 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2004-09-15 EP disclosed
US-6268444-B1 TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION DOW CHEMICAL COMPANY 2001-07-31 US disclosed