Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 4/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917719 | 0.84 | GABBR2 (0.52) | NPSR1CYP1A2HMGCRGPR55NR1I2 | |
| SCHEMBL6910734 | 0.82 | HMGCR (0.47) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL9389232 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL6910755 | 0.78 | GAA (0.49) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL9513470 | 0.77 | HMGCR (0.50) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL5663893 | 0.77 | RXRA (0.38) | HMGCR | |
| SCHEMBL6916387 | 0.77 | LMNA (0.47) | MEN1KMT2ANPSR1ALDH1A1CYP3A4 | |
| SCHEMBL9224042 | 0.76 | GABBR2 (0.47) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL6914359 | 0.76 | HMGCR (0.50) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL9224571 | 0.75 | GAA (0.49) | MEN1KMT2AALDH1A1HMGCRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | claimed |