Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399040 | 0.85 | KIF11 (0.45) | KIF11ALDH1A1MAPTPTGS1TSHR | |
| SCHEMBL21086716 | 0.85 | KIF11 (0.42) | KIF11ALDH1A1MAPTTSHRNPC1 | |
| SCHEMBL4399038 | 0.85 | KIF11 (0.45) | KIF11ALDH1A1MAPTPTGS1TSHR | |
| SCHEMBL27685329 | 0.84 | KIF11 (0.50) | KIF11ALDH1A1MAPTPTGS1 | |
| SCHEMBL4401812 | 0.84 | KIF11 (0.50) | KIF11ALDH1A1MAPTPTGS1 | |
| SCHEMBL4401809 | 0.84 | KIF11 (0.50) | KIF11ALDH1A1MAPTPTGS1 | |
| SCHEMBL23176910 | 0.83 | KIF11 (0.45) | KIF11ALDH1A1MAPTPTGS1SLC1A3 | |
| SCHEMBL27644364 | 0.83 | GRIN2D (0.47) | KIF11ALDH1A1MAPTPTGS1NPC1 | |
| SCHEMBL6670877 | 0.83 | KIF11 (0.45) | KIF11ALDH1A1MAPTPTGS1NPC1 | |
| SCHEMBL6670880 | 0.83 | KIF11 (0.45) | KIF11ALDH1A1MAPTPTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566494-B1 | CXCR4 RECEPTOR COMPOUNDS | ACER THERAPEUTICS INC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20160159861-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-20160159861-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-9155795-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9155795-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9096646-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096646-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| WO-2015010045-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150011466-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS INC (US) | 2015-01-08 | — | — | US | disclosed |
| US-20150011466-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS INC (US) | 2015-01-08 | — | — | US | disclosed |
| US-20110300167-A1 | CXCR5 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
| WO-2011106703-A2 | CXCR4 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2010053547-A2 | CXCR5 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053550-A2 | CXCR4 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053546-A2 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053545-A2 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | KIF11 3925/4885ALDH1A1 4713/4885MAPT 683/4885 |
| US-20150011466-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | KIF11 2633/4885ALDH1A1 3645/4885MAPT 2434/4885 |
| US-20110300167-A1 | CXCR5 RECEPTOR COMPOUNDS | CXCR5, CXCR1, CCR5 | KIF11 2852/4885ALDH1A1 4843/4885MAPT 4577/4885 |
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | CRHR1, CRH, CRHR2 | KIF11 3271/4885ALDH1A1 4197/4885MAPT 1149/4885 |
| US-20160159861-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | KIF11 2633/4885ALDH1A1 3645/4885MAPT 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.