Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879821 | 0.81 | HTR5A (0.50) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL14414488 | 0.80 | EGLN1 (0.51) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11497619 | 0.80 | HDAC6 (0.47) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL643810 | 0.79 | KDM4E (0.54) | HTR5AHDAC6MAPTALDH1A1KDM4E | |
| SCHEMBL20138518 | 0.77 | HDAC6 (0.60) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL14288545 | 0.77 | HTR5A (0.60) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL15625164 | 0.77 | HDAC6 (0.64) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| Water SCHEMBL15271605 | 0.77 | MMP2 (0.52) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL661556 | 0.76 | HTR5A (0.52) | HTR5AHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL1285337 | 0.76 | HDAC6 (0.52) | HTR5AHDAC6ALDH1A1LMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| US-10036971-B2 | Charging member, process cartridge, and electrophotographic image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-07-31 | — | — | US | disclosed |
| US-10036971-B2 | Charging member, process cartridge, and electrophotographic image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-07-31 | — | — | US | disclosed |
| US-9885971-B2 | Charging member, process cartridge, and electrophotographic image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-02-06 | — | — | US | disclosed |
| US-9885971-B2 | Charging member, process cartridge, and electrophotographic image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-02-06 | — | — | US | disclosed |
| US-20160378011-A1 | CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20160299450-A1 | CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160299450-A1 | CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160299451-A1 | CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160299451-A1 | CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20150331348-A1 | CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-11-19 | — | — | US | disclosed |
| US-20150331348-A1 | CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-11-19 | — | — | US | disclosed |
| WO-2015032286-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | F.HOFFMANN-LA ROCHE AG (CH) | 2015-03-12 | — | — | WO | disclosed |
| WO-2011049731-A1 | QUINOLINONE-PYRAZOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10036971-B2 | Charging member, process cartridge, and electrophotographic image forming apparatus | GNG2, NRAS, ARFGEF1 | HTR5A 3462/4885HDAC6 3703/4885MAPT 3572/4885 |
| US-20150331348-A1 | CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | GNG2, NRAS, ARFGEF1 | HTR5A 3462/4885HDAC6 3703/4885MAPT 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.