SCHEMBL6914499

SCHEMBL6914499

CC(NC(=O)OCc1ccccc1)C(=O)NCCP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
CTSK P43235 2/20 0.54
TPSAB1 Q15661 2/20 0.53
PLG P00747 1/20 0.53
PRSS1 P07477 1/20 0.53
ELANE P08246 2/20 0.51
PRTN3 P24158 1/20 0.51
MME P08473 2/20 0.51
ECE1 P42892 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9136357 0.88 CTSK (0.62) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL4075738 0.86 CYP1A2 (0.62) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL15318479 0.85 CA5A (0.62) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL10954836 0.85 CA5A (0.62) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL11702018 0.85 CYP1A2 (0.58) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL8502694 0.85 CYP1A2 (0.58) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL10957418 0.85 CYP1A2 (0.58) CYP1A2CTSKTPSAB1PLGPRSS1
SCHEMBL11567663 0.84 CTSK (0.57) CYP1A2CTSKELANEPRTN3MME
SCHEMBL11030901 0.84 CTSK (0.57) CYP1A2CTSKELANEPRTN3MME
SCHEMBL11568471 0.84 CTSK (0.57) CYP1A2CTSKELANEPRTN3MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6762174-B1 BETA-ALETHINE WITH MELPHALAN OR CYCLOPHOSPHAMIDE; PREVENTS CLINICAL APPEARANCE OF A NEOPLASTIC OR PRE-NEOPLASTIC CONDITION; IMMUNOMODULATION; ENHANCING CELL GROWTH, VITALITY, DIFFERENTIATION; ANTISENESCENCE DOVETAIL TECHNOLOGIES, INC. 2004-07-13 US disclosed
US-6498150-B2 USEFUL IN ENHANCING VACCINATION, INCREASING SYNTHESIS AND FUNCTION OF BLOOD CELL COMPONENTS, AND ENHANCING ANTITUMOR EFFECTS DOVETAIL TECHNOLOGIES, INC. 2002-12-24 US disclosed
US-6451853-B1 Small molecules that elicit a polarized Th1 response and for modulation of cellular immunity DOVETAIL TECHNOLOGIES, INC 2002-09-17 US disclosed
US-20020035118-A1 LOW MOLECULAR WEIGHT CELL, BONE MARROW AND IMMUNE STIMULANTS DOVETAIL TECHNOLOGIES INC. 2002-03-21 US disclosed
US-6007819-A Methods of inducing immunity using low molecular weight immune stimulants DOVETAIL TECHNOLOGIES, INC. (US) 1999-12-28 US disclosed
WO-1999042099-A1 LOW MOLECULAR WEIGHT COMPOUNDS ADMINISTERED TOGETHER WITH ANTI-CANCER AGENTS TO TREAT CANCER AND PHARMACEUTICAL COMPOSITIONS THEREOF DOVETAIL TECHNOLOGIES INC. (US) 1999-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035118-A1 LOW MOLECULAR WEIGHT CELL, BONE MARROW AND IMMUNE STIMULANTS ACP1, CD14, HPGDS CYP1A2 4785/4885CTSK 1049/4885TPSAB1 3131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.