Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cymene SCHEMBL8393048 | 0.81 | ACHE (0.48) | LMNAPTGS1TRPA1CACNA1CTYR | |
| SCHEMBL1132573 | 0.81 | KIF11 (0.45) | LMNATYRNPC1RAB9ANOTUM | |
| SCHEMBL2692675 | 0.81 | HDAC3 (0.40) | LMNAPTGS1TRPA1CACNA1CNPC1 | |
| SCHEMBL197335 | 0.80 | KIF11 (0.52) | LMNATYRNPC1RAB9ANOTUM | |
| SCHEMBL3819772 | 0.80 | LMNA (0.38) | LMNAPTGS1TRPA1CACNA1CTYR | |
| Iodide SCHEMBL30804631 | 0.79 | KIF11 (0.44) | LMNATYRNPC1RAB9ANOTUM | |
| Iodide SCHEMBL28367770 | 0.79 | KIF11 (0.44) | LMNATYRNPC1RAB9ANOTUM | |
| P-Cymene SCHEMBL1143 | 0.77 | ACHE (0.53) | LMNAPTGS1TRPA1CACNA1CTYR | |
| P-Cymene SCHEMBL1697748 | 0.77 | ACHE (0.53) | LMNAPTGS1TRPA1CACNA1CTYR | |
| SCHEMBL29628971 | 0.77 | RXRA (0.53) | PTGS2KIF11PTPN5RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100436490-C | Polymerization catalyst for alpha-olefin, novel transition metal compound and catalyst component, and process for producing polymer | MITSUBISHI CHEM CORP (JP) | 2008-11-26 | — | — | CN | disclosed |
| US-6825371-B2 | CATALYST FOR POLYMERIZATION OF ALPHA -OLEFIN, WHICH COMPRISES: AN ESSENTIAL COMPONENT (A) OF A TRANSITION METAL COMPOUND, AN ESSENTIAL COMPONENT (B) OF AN ION EXCHANGEABLE LAYER COMPOUND EXCEPT FOR SILICATE, OR AN INORGANIC SILICATE, AND OPTIONAL | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030166459-A1 | Catalysts for polymerization of alpha-olefins, process for producing alpha-olefin polymers, novel transition metal compounds and catalyst components for polymerization of alpha-olefin | MITSUBISHI CHEMICAL CORPORATION | 2003-09-04 | — | — | US | disclosed |
| US-6590045-B2 | An alpha-olefin polymerization catalysts consists of a transition metal compound; an ion exchangable layer compound except for silicate, or an inorganic silicate | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1312619-A2 | Catalyst for the polymerisation of alpha olefins | Mitsubishi Chemical Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-20020045535-A1 | Catalysts for polymerization of alpha-olefins, process for producing alpha-olefin polymers, novel transition metal compounds and catalyst components for polymerization of alpha-olefin | MITSUBISHI CHEMICAL CORPORATION. | 2002-04-18 | — | — | US | disclosed |
| US-6344530-B2 | POLYMERIZATION CATALYST OF A TRANSITION METAL COMPOUND, AN ION EXCHANGEABLE LAYER OR AN INORGANIC SILICATE AND AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| US-6340652-B1 | AS POLYMERIZATION CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| US-20010034425-A1 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION | 2001-10-25 | — | — | US | disclosed |
| US-6252097-B1 | Transition metal compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-06-26 | — | — | US | disclosed |
| CN-1189506-A | Catalyst for polymerizing alpha-olefin, process for producing alpha-olefin polymer, novel transition metal compound for polymerizing alpha-olefin and catalyst component | MITSUBISHI CHEM CORP (JP) | 1998-08-05 | — | — | CN | disclosed |
| EP-0846696-A1 | Catalyst for polymerization of alpha-olefins | Mitsubishi Chemical Corporation (JP) | 1998-06-10 | — | — | EP | disclosed |