Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 13/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 2/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27427059 | 0.81 | HPN (0.49) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6914648 | 0.81 | HMGCR (0.43) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6918005 | 0.80 | VCAM1 (0.40) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6916387 | 0.78 | LMNA (0.47) | MAPTCA1CA2HMGCRGPR55 | |
| SCHEMBL6917312 | 0.76 | ALOX15 (0.50) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6917308 | 0.75 | ALOX15 (0.49) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6917719 | 0.74 | GABBR2 (0.52) | HMGCRGPR55NR1I2 | |
| SCHEMBL9225348 | 0.73 | LMNA (0.43) | VCAM1CA1CA2HMGCRGPR55 | |
| SCHEMBL6915809 | 0.73 | HMGCR (0.38) | VCAM1CA1CA2HMGCRGPR55 | |
| SCHEMBL6910755 | 0.73 | GAA (0.49) | MAPTHMGCRGPR55NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | claimed |