Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918968 | 0.81 | MEN1 (0.42) | MEN1KMT2ATP53MAPT | |
| SCHEMBL6834200 | 0.72 | MEN1 (0.51) | GPR27AVPR2MEN1KMT2AMETAP2 | |
| SCHEMBL6919399 | 0.71 | METAP2 (0.60) | GPR27AVPR2MEN1KMT2AMAPT | |
| SCHEMBL6818410 | 0.70 | GPR27 (0.48) | GPR27AVPR2MEN1KMT2AMCL1 | |
| SCHEMBL6818370 | 0.67 | METAP2 (0.44) | MEN1KMT2AMAPTMETAP2 | |
| SCHEMBL7061066 | 0.66 | — | — | |
| SCHEMBL6819170 | 0.65 | MEN1 (0.44) | MEN1KMT2AMAPTMETAP2PKM | |
| SCHEMBL25171022 | 0.65 | ALDH1A1 (0.44) | MEN1KMT2AMCL1TP53MAPT | |
| SCHEMBL7124908 | 0.64 | ABCG2 (0.38) | MEN1KMT2A | |
| SCHEMBL11584745 | 0.64 | KMT2A (0.60) | MEN1KMT2AMCL1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |