Phenol

Phenol

SCHEMBL691965

Cc1cc(O)c(C(C)C)cc1C.Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
ALDH1A1 P00352 4/20 0.51
GAA P10253 3/20 0.51
HTT P42858 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MAPT P10636 4/20 0.50
NPSR1 Q6W5P4 3/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 4/20 0.49
CYP3A4 P08684 3/20 0.49
CYP2C19 P33261 3/20 0.49
CYP2D6 P10635 3/20 0.49
CYP2C9 P11712 2/20 0.49
ALOX15 P16050 2/20 0.49
HIF1A Q16665 2/20 0.49
PKM P14618 2/20 0.49
THRB P10828 1/20 0.49
TRPA1 O75762 1/20 0.47
CHRM1 P11229 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214157 0.85 LMNA (0.68) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL29872559 0.85 LMNA (0.68) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL9556365 0.83 LMNA (0.65) LMNAALDH1A1GAAHTTHSD17B10
Thymol SCHEMBL252621 0.79 TRPA1 (0.78) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL25906326 0.78 HSP90AA1 (0.55) LMNAALDH1A1GAAHTTHSD17B10
Phenol SCHEMBL27532020 0.78 GABRA1 (0.52) LMNAALDH1A1GAAHTTHSD17B10
Phenol SCHEMBL27630840 0.77 GABRA1 (0.61) LMNAALDH1A1GAAHSD17B10MAPT
SCHEMBL9615467 0.77 LMNA (0.49) LMNAALDH1A1GAAHTTHSD17B10
Phenol SCHEMBL28870687 0.76 CA12 (0.65) LMNAALDH1A1HTTHSD17B10CYP1A2
Phenol SCHEMBL5677167 0.75 GABRA1 (0.82) LMNAALDH1A1HSD17B10MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107383087-A For preparing the high selective method of organodiphosphite 英威达纺织(英国)有限公司 2017-11-24 CN disclosed
EP-2421875-B1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA TECHNOLOGIES SARL (CH) 2017-08-23 EP disclosed
EP-2421876-B1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA Technologies S à r l (CH) 2016-07-27 EP disclosed
US-8772549-B2 Highly selective process for producing organodiphosphites INVISTA North America S.à r.l. (US) 2014-07-08 US disclosed
US-8609901-B2 Highly selective process for producing organodiphosphites INVISTA NORTH AMERICA S.A R.L. (US) 2013-12-17 US disclosed
EP-2421876-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES Invista Technologies S.A R.L. (CH) 2012-02-29 EP disclosed
EP-2421875-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES Invista Technologies S.A R.L. (CH) 2012-02-29 EP disclosed
WO-2010123747-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA TECHNOLOGIES S.A R.L. (CH) 2010-10-28 WO disclosed
WO-2010123743-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA TECHNOLOGIES S.A R.L. (CH) 2010-10-28 WO disclosed
US-20100267991-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA NORTH AMERICA S.A.R.L. (US) 2010-10-21 US disclosed
US-20100267990-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA NORTH AMERICA S.A R.L. (US) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267990-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES AGPS, FDPS, DCPS LMNA 4819/4885ALDH1A1 3128/4885GAA 920/4885
US-20100267991-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES AGPS, FDPS, DCPS LMNA 4819/4885ALDH1A1 3128/4885GAA 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.