SCHEMBL9615467

SCHEMBL9615467

Cc1cc(O)c(C(C)C)cc1C(c1ccccc1)c1cc(C(C)C)c(O)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.49
ALDH1A1 P00352 4/20 0.48
GAA P10253 3/20 0.48
HTT P42858 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPT P10636 4/20 0.47
NPSR1 Q6W5P4 3/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 3/20 0.46
CYP3A4 P08684 3/20 0.46
CYP2C19 P33261 3/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
ALOX15 P16050 2/20 0.46
HIF1A Q16665 2/20 0.46
PKM P14618 2/20 0.46
THRB P10828 1/20 0.46
TYR P14679 1/20 0.45
TRPA1 O75762 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4060913 0.85 TYR (0.42) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL5612635 0.84 ALDH1A1 (0.45) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL353293 0.83 GABRA1 (0.57) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL12415068 0.81 LMNA (0.47) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL1245089 0.79 LMNA (0.65) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL30411784 0.79 LMNA (0.65) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL8990374 0.79 TYR (0.61) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL28532546 0.79 MAPT (0.60) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL1697841 0.77 ALDH1A1 (0.44) LMNAALDH1A1GAAHTTHSD17B10
SCHEMBL5372483 0.77 ALOX15 (0.56) LMNAALDH1A1HTTHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4142331-A None JP disclosed
JP-H04142331-A POLYFORMAL RESIN, ITS PREPARATION AND RAW MATERIAL FOR OPTICAL INSTRUMENT COMPRISING SAME IDEMITSU KOSAN CO LTD 1992-05-15 JP disclosed