Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.35 |
| ▸ | JAK1 | P23458 | 5/20 | 0.35 |
| ▸ | TYK2 | P29597 | 5/20 | 0.35 |
| ▸ | JAK3 | P52333 | 5/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175493 | 0.84 | PGR (0.41) | JAK2JAK1TYK2JAK3PSIP1 | |
| SCHEMBL6922734 | 0.82 | PSIP1 (0.35) | JAK2JAK1TYK2JAK3PSIP1 | |
| SCHEMBL6921397 | 0.70 | PPOX (0.34) | BRD4 | |
| SCHEMBL7987004 | 0.67 | PSIP1 (0.33) | PSIP1PGRBRD4 | |
| SCHEMBL6662068 | 0.67 | PSIP1 (0.47) | JAK2JAK1TYK2JAK3PSIP1 | |
| SCHEMBL6174842 | 0.67 | PGR (0.41) | JAK2JAK1TYK2JAK3PSIP1 | |
| SCHEMBL10521335 | 0.66 | PSIP1 (0.36) | JAK2JAK1TYK2JAK3PSIP1 | |
| SCHEMBL10612189 | 0.66 | L3MBTL1 (0.43) | — | |
| SCHEMBL31047810 | 0.65 | PSIP1 (0.51) | JAK2JAK1TYK2JAK3PSIP1 | |
| SCHEMBL6174302 | 0.65 | MEN1 (0.39) | PGRNR3C1AREGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048348-A1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI) ONES USED AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | WO | disclosed |