Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921397 | 0.89 | PPOX (0.34) | MAPK14ALOX15TSHRBRD4 | |
| SCHEMBL6174842 | 0.84 | PGR (0.41) | PSIP1PGRJAK2JAK1TYK2 | |
| SCHEMBL6920368 | 0.82 | JAK2 (0.35) | PSIP1PGRJAK2JAK1TYK2 | |
| SCHEMBL10414302 | 0.75 | PPOX (0.46) | MAPK14BRD4 | |
| SCHEMBL7891358 | 0.74 | L3MBTL1 (0.38) | HTR1A | |
| SCHEMBL7987004 | 0.74 | PSIP1 (0.33) | PSIP1PGRBRPF1BRD4 | |
| SCHEMBL6174205 | 0.72 | PGR (0.34) | PGRHTR1ABRD4 | |
| SCHEMBL10624240 | 0.68 | L3MBTL1 (0.54) | MAPK14 | |
| SCHEMBL6662068 | 0.67 | PSIP1 (0.47) | PSIP1PGRJAK2JAK1TYK2 | |
| SCHEMBL6175493 | 0.67 | PGR (0.41) | PSIP1PGRJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048348-A1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI) ONES USED AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | WO | disclosed |