Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30221865 | 1.00 | MAPT (0.44) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL27864267 | 0.89 | SMN1; SMN2 (0.39) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13785257 | 0.86 | MAPT (0.42) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL21082922 | 0.82 | MAPT (0.48) | MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL10316763 | 0.80 | TDP1 (0.50) | MAPTKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL2470925 | 0.80 | TSHR (0.49) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL31510411 | 0.80 | TDP1 (0.50) | MAPTKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL128166 | 0.77 | TSHR (0.45) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13680343 | 0.77 | MAPT (0.51) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14159396 | 0.77 | MAPT (0.46) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036299-B2 | Compositions containing direct dyes for imparting color and tone to the hair | L'OREAL (FR) | 2024-07-16 | — | — | US | claimed |
| US-11737964-B2 | Hair color toning compositions, methods of use, and kits | L'OREAL (FR) | 2023-08-29 | — | — | US | claimed |
| US-20230099740-A1 | HAIR COLOR TONING COMPOSITIONS, METHODS OF USE, AND KITS | L'OREAL (FR) | 2023-03-30 | — | — | US | claimed |
| WO-2022189412-A1 | HAIR COLORING COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A NONIONIC AMINO DIRECT DYE | L'OREAL (FR) | 2022-09-15 | — | — | WO | claimed |
| US-20210369582-A1 | METHODS AND COMPOSITIONS FOR REMOVING COLOR FROM COLOR-TREATED HAIR | L'OREAL (FR) | 2021-12-02 | — | — | US | claimed |
| US-11173102-B1 | Methods and compositions for removing color from color-treated hair | L'OREAL (FR) | 2021-11-16 | — | — | US | claimed |
| US-11154479-B1 | Methods of removing color from color-treated hair | L'OREAL (FR) | 2021-10-26 | — | — | US | claimed |
| CN-112955112-A | Two-component system for artificial hair coloring | 汉高股份有限及两合公司 | 2021-06-11 | — | — | CN | claimed |
| US-9993413-B2 | Keratin fibre dyeing composition | BEAUTY & BUSINESS S.P.A. (IT) | 2018-06-12 | — | — | US | claimed |
| EP-2658511-B1 | DYEING COMPOSITION FOR KERATIN FIBERS | KAO GERMANY GMBH (DE) | 2018-04-04 | — | — | EP | claimed |
| US-20100189670-A1 | METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | US | claimed |
| US-7736633-B2 | Method for enhancing effects of colorants and conditioners | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-15 | — | — | US | claimed |
| US-20090074694-A1 | DYED-HAIR-BINDING PEPTIDES AND PEPTIDE-BASED HAIR REAGENTS FOR PERSONAL CARE | AFFINERGY, LLC. | 2009-03-19 | — | — | US | claimed |
| CN-101282705-A | Method for enhancing effects of colorants and conditioners | DU PONT (US) | 2008-10-08 | — | — | CN | claimed |
| US-7419656-B2 | Mixture containing phenylenediamine compound | KAO CORPORATION (JP) | 2008-09-02 | — | — | US | claimed |
| EP-1928397-A1 | METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS | E.I.Du pont de nemours and company (US) | 2008-06-11 | — | — | EP | claimed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | claimed |
| EP-1844816-A2 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'Oréal (FR) | 2007-10-17 | — | — | EP | claimed |
| WO-2007038733-A1 | METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-05 | — | — | WO | claimed |
| US-20070067924-A1 | Method for enhancing effects of colorants and conditioners | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-03-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737964-B2 | Hair color toning compositions, methods of use, and kits | CUTA, TAAR5, SHH | MAPT 3653/4885KMT2A 1404/4885ALDH1A1 2063/4885 |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | MAPT 361/4885KMT2A 1545/4885ALDH1A1 18/4885 |
| US-12036299-B2 | Compositions containing direct dyes for imparting color and tone to the hair | PHOSPHO1, TYR, AADAT | MAPT 812/4885KMT2A 120/4885ALDH1A1 1243/4885 |
| US-20090074694-A1 | DYED-HAIR-BINDING PEPTIDES AND PEPTIDE-BASED HAIR REAGENTS FOR PERSONAL CARE | TAP1, RBP1, CUTA | MAPT 2870/4885KMT2A 2305/4885ALDH1A1 2063/4885 |
| US-11173102-B1 | Methods and compositions for removing color from color-treated hair | TYR, POLR1C, CYCS | MAPT 2581/4885KMT2A 1605/4885ALDH1A1 1854/4885 |
| US-20230099740-A1 | HAIR COLOR TONING COMPOSITIONS, METHODS OF USE, AND KITS | CUTA, TAAR5, SHH | MAPT 3653/4885KMT2A 1404/4885ALDH1A1 2063/4885 |
| US-11154479-B1 | Methods of removing color from color-treated hair | TYR, IK, HLA-C | MAPT 2434/4885KMT2A 670/4885ALDH1A1 959/4885 |
| US-20210369582-A1 | METHODS AND COMPOSITIONS FOR REMOVING COLOR FROM COLOR-TREATED HAIR | TYR, POLR1C, CYCS | MAPT 2581/4885KMT2A 1605/4885ALDH1A1 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.