Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828766 | 0.81 | HSD11B1 (0.33) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL5510640 | 0.81 | CA1 (0.35) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL483018 | 0.78 | SMN1; SMN2 (0.34) | ALDH1A1TSHRSMN1; SMN2TDP1LMNA | |
| SCHEMBL692167 | 0.78 | TTR (0.38) | TSHRSMN1; SMN2 | |
| SCHEMBL693708 | 0.77 | ALDH1A1 (0.31) | ALDH1A1TSHRCYP3A4THRBHPGD | |
| SCHEMBL696313 | 0.77 | TSHR (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL458583 | 0.77 | TTR (0.41) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5146133 | 0.76 | HTR6 (0.46) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5152547 | 0.74 | GABRA1 (0.39) | ALDH1A1TSHRSMN1; SMN2THRB | |
| SCHEMBL10936452 | 0.74 | CES1 (0.30) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071985-B1 | WATER-SOLUBLE MONO-AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0071985-A2 | Water-soluble mono-azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | claimed |
| US-4260776-A | PYRAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | claimed |
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7988740-B2 | Keratin dyeing compositions comprising a radical scavenger and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-02 | — | — | US | disclosed |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |
| EP-0072557-B1 | WATER-SOLUBLE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |
| EP-0071985-B1 | WATER-SOLUBLE MONO-AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |
| EP-0072557-A2 | Water-soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-23 | — | — | EP | disclosed |
| EP-0071985-A2 | Water-soluble mono-azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| US-4260776-A | PYRAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-3891618-A | Azo-dyestuffs containing {60 ,{62 -dichloropropionylamino or {60 ,{62 -dibromopropionylamino groups | CIBA GEIGY AG | 1975-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | KRT18, LPO, CYB5R3 | ALDH1A1 326/4885TSHR 4803/4885SMN1; SMN2 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.