Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533196 | 0.85 | SLC6A3 (0.47) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL15533197 | 0.85 | SLC6A3 (0.47) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8770872 | 0.84 | LMNA (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL692174 | 0.84 | LMNA (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6777080 | 0.84 | SLC6A3 (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL12268259 | 0.83 | ALDH1A1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL22703334 | 0.83 | CYP1A2 (0.41) | LMNAALDH1A1SMN1; SMN2TNFRAB9A | |
| SCHEMBL27462122 | 0.83 | ALDH1A1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL5720979 | 0.82 | SLC6A3 (0.40) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL3658423 | 0.82 | L3MBTL1 (0.46) | LMNASLC6A3L3MBTL1TSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844044-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-04-02 | — | — | US | disclosed |
| US-7041667-B1 | CCR5 modulators | PFIZER, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1013276-A1 | Aminoazacycloalkanes as CCR5 modulators | PFIZER INC. (US) | 2000-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | LMNA 2317/4885ALDH1A1 3586/4885HTT 1454/4885 |
| US-10844044-B2 | WDR5 inhibitors and modulators | WDR5, WDR1, WDR3 | LMNA 2328/4885ALDH1A1 3517/4885HTT 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.